{"id":57296,"date":"2025-01-08T10:00:00","date_gmt":"2025-01-08T18:00:00","guid":{"rendered":"https:\/\/foodrevolution.org\/?p=57296"},"modified":"2026-09-15T00:59:10","modified_gmt":"2026-09-15T07:59:10","slug":"can-we-train-our-taste-buds","status":"publish","type":"post","link":"https:\/\/foodrevolution.org\/blog\/can-we-train-our-taste-buds\/","title":{"rendered":"Can We Train Our Taste Buds for Better Health?"},"content":{"rendered":"<p><b>By Monica Dus \u2022 Originally published by <\/b><a href=\"https:\/\/theconversation.com\/can-we-train-our-taste-buds-for-health-a-neuroscientist-explains-how-genes-and-diet-shape-taste-205456\"><b>The Conversation<\/b><\/a><\/p>\n<p>Have you ever wondered why only hummingbirds sip nectar from feeders?<\/p>\n<p>Unlike sparrows, finches, and most other birds, hummingbirds <a href=\"https:\/\/ww2.aip.org\/inside-science\/why-hummingbirds-have-a-sweet-tooth\">can taste sweetness<\/a> because they <a href=\"https:\/\/doi.org\/10.1126\/scisignal.2005818\">carry the genetic instructions<\/a> necessary to detect sugar molecules.<\/p>\n<p>Like hummingbirds, humans can sense sugar because our DNA contains gene sequences coding for the <a href=\"https:\/\/theconversation.com\/a-taste-for-sweet-an-anthropologist-explains-the-evolutionary-origins-of-why-youre-programmed-to-love-sugar-173197\">molecular detectors<\/a> that allow us to detect sweetness.<\/p>\n<p>But it\u2019s more complex than that. Our ability to sense sweetness, as well as other tastes, involves a delicate dance between our genetic makeup and the foods we encounter from the womb to the dinner table.<\/p>\n<p>Neuroscientists <a href=\"https:\/\/scholar.google.com\/citations?user=2LAmkegAAAAJ&amp;hl=en\">like me<\/a> are working to decipher how this intricate <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11154-016-9360-5\">interplay between genes and diet<\/a> shapes taste.<\/p>\n<p>In <a href=\"https:\/\/sites.lsa.umich.edu\/dus-lab\/\">my laboratory<\/a> at the University of Michigan, we are diving deeply into one specific aspect: how <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(22)01212-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS096098222201212X%3Fshowall%3Dtrue\">consuming too much sugar dulls the sense of sweetness<\/a>. <strong>Taste is so central to our eating habits that understanding how genes and the environment shape it has crucial implications <a href=\"http:\/\/health.euroafrica.org\/books\/dietnutritionwho.pdf\">for nutrition<\/a>, <a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240039919\">food science<\/a>, and <a href=\"https:\/\/doi.org\/10.1093\/ajcn\/nqaa302\">disease prevention<\/a>.<\/strong><\/p>\n<h2>The Role of Genes in Sensing Taste<\/h2>\n<p>As with hummingbirds, the <a href=\"https:\/\/www.webmd.com\/diet\/features\/science-how-we-taste\">human ability to discern what food tastes like<\/a> depends on the presence of taste receptors. These molecular detectors are found on sensory cells housed inside the taste buds, the sensory organs on the tongue&#8217;s surface.<\/p>\n<p>The <a href=\"https:\/\/theconversation.com\/a-taste-for-sweet-an-anthropologist-explains-the-evolutionary-origins-of-why-youre-programmed-to-love-sugar-173197\">interactions between taste receptors and food molecules<\/a> give rise to the five basic taste qualities: sweetness, savoriness, bitterness, saltiness, and sourness. These qualities are transmitted from the mouth to the brain via specific nerves.<\/p>\n<p>For instance, when sugar binds to the sweet receptor, it signals sweetness. Our innate preference for the taste of some foods over others is rooted in how the tongue and the brain <a href=\"https:\/\/doi.org\/10.1038\/486S16a\">became wired during our evolutionary history<\/a>. Taste qualities signaling the presence of essential nutrients and energy, like salt and sugar, send information to brain areas linked to pleasure. Conversely, tastes that alert us to potentially harmful substances, such as the bitterness of certain toxins, are connected to those that make us <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(13)00418-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982213004181%3Fshowall%3Dtrue\">feel discomfort or pain<\/a>.<\/p>\n<p><strong>While the presence of genes encoding for functional taste receptors in our DNA allows us to <a href=\"https:\/\/doi.org\/10.1038\/486S16a\">detect food molecules<\/a>, how we respond to these also depends on the unique combination of taste genes we carry.<\/strong> Like ice cream, genes, including those for taste receptors, come in different flavors.<\/p>\n<p>Take, for instance, a taste receptor for bitterness called TAS2R38. Scientists <a href=\"https:\/\/doi.org\/10.3389%2Ffgene.2019.01272\">found small changes in the genetic code<\/a> for the TAS2R38 gene among different people. These genetic variants affect how people perceive the <a href=\"\/blog\/bitter-is-better-why-bitter-foods-can-be-good-for-your-health\/\">bitterness of vegetables<\/a>, berries, and wine.<\/p>\n\n      <div class=\"youtube-video\">\n        <div class=\"d-print-none embed-youtube-wrapper mb-3\">\n          <div class=\"embed-youtube ratio ratio-16x9 \">\n            <iframe class=\"\" src=\"https:\/\/www.youtube.com\/embed\/C4rdqXXzPGU?rel=0\" allowfullscreen\"><\/iframe>\n          <\/div>\n          <div class=\"video-caption mt-2 container-fluid\">\n            <div class=\"row justify-content-center\">\n              <div class=\"col-10\">\n                <p class=\"mb-0 text-center\"><i><\/i><\/p>\n              <\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n        <div class=\"d-none d-print-inline\">\n          <p><i class=\"fab fa-youtube mr-2\"><\/i><span class=\"print-link\">https:\/\/www.youtube.com\/watch?v=C4rdqXXzPGU<\/a><\/p>\n        <\/div>\n      <\/div>\n    \n<p><em>Video Caption: Aside from allowing us to taste the wide variety of flavors in foods, taste also helps us distinguish between foods that are healthy or potentially harmful, such as spoiled milk.<\/em><\/p>\n<p>Follow-up studies have suggested a link between those same variants and food choice, particularly for <a href=\"https:\/\/www.reuters.com\/article\/us-alcohol-taste-genes\/genes-influence-taste-and-possibly-use-of-alcohol-idINKCN0HL23U20140926\">vegetable and alcohol consumption<\/a>.<\/p>\n<p>Many more variants exist in our gene repertoire, including those for the sweet taste receptor. However, whether or not and how these genetic differences <a href=\"https:\/\/doi.org\/10.1016\/j.cofs.2021.07.001\">affect our taste and eating habits<\/a> is still being worked out. What is certain is that <strong>while genetics lays the groundwork for taste sensations and preferences, experiences with food can profoundly reshape them.<\/strong><\/p>\n<h2>How Diet Influences Taste<\/h2>\n<figure id=\"attachment_57301\" aria-describedby=\"caption-attachment-57301\" style=\"width: 1233px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-57301\" src=\"https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-185279377.jpg\" alt=\"A close-up of a biracial toddler drinking orange juice in the kitchen.\" width=\"1233\" height=\"851\" srcset=\"https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=1233,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-185279377.jpg 1233w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=300,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-185279377-300x207.jpg 300w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=1024,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-185279377-1024x707.jpg 1024w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=768,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-185279377-768x530.jpg 768w\" sizes=\"auto, (max-width: 1233px) 100vw, 1233px\" \/><figcaption id=\"caption-attachment-57301\" class=\"wp-caption-text\">iStock.com\/Lostinbids<\/figcaption><\/figure>\n<p>Many of our innate sensations and preferences are molded by our <a href=\"https:\/\/www.npr.org\/2011\/08\/08\/139033757\/babys-palate-and-food-memories-shaped-before-birth\">early experiences with food<\/a>, sometimes before we\u2019re even born. Some molecules from the mother\u2019s diet, like garlic or carrots, reach the <a href=\"https:\/\/www.npr.org\/2011\/08\/08\/139033757\/babys-palate-and-food-memories-shaped-before-birth\">fetus\u2019s developing taste buds via the amniotic fluid<\/a> and can affect the appreciation of these foods after birth.<\/p>\n<p>Infant formula can also influence food preferences later on. For example, research shows that infants fed with formulas that are not based on cow\u2019s milk \u2014 which are more bitter and sour because of their amino acid content \u2014 are more accepting of bitter, sour, and savory foods such as vegetables after weaning than <a href=\"https:\/\/doi.org\/10.3945\/ajcn.2009.27462o\">those who consume cow milk-based formula<\/a>. And <strong><a href=\"https:\/\/theconversation.com\/why-kids-shouldnt-eat-added-sugar-before-they-turn-2-according-to-a-nutritional-epidemiologist-173398\">toddlers who drink sweetened water<\/a> strongly prefer <a href=\"https:\/\/doi.org\/10.1007%2Fs11154-016-9360-5\">sweet beverages as early as age two<\/a>.<\/strong><\/p>\n<p>The effect of food on our taste predispositions doesn\u2019t stop in early life. <a href=\"https:\/\/www.cell.com\/trends\/endocrinology-metabolism\/fulltext\/S1043-2760(20)30235-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1043276020302356%3Fshowall%3Dtrue\">What we eat as adults<\/a>, especially our sugar and salt intake, can also shape how we perceive and potentially choose food. <a href=\"https:\/\/media.nutrition.org\/wp-content\/uploads\/2020\/01\/NIH-Workshop-Slides-Beauchamp.pdf\">Cutting down on sodium<\/a> in our diet decreases our preferred level of saltiness, whereas consuming more makes us like saltier foods.<\/p>\n<p>Something similar occurs with sugar: <a href=\"https:\/\/doi.org\/10.3945\/ajcn.115.112300\">Reduce sugar in your diet<\/a>, and you may find food sweeter. Conversely, as <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(22)01212-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS096098222201212X%3Fshowall%3Dtrue\">research in rats<\/a> and <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(19)30492-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124719304929%3Fshowall%3Dtrue\">flies<\/a> suggests (<i>Editor\u2019s Note: Our view on animals in medical research is <\/i><a href=\"https:\/\/support.foodrevolution.org\/article\/24-animal-testing\"><i>here<\/i><\/a>), high sugar levels may dull your sensation of sweetness.<\/p>\n<p>Although researchers are still working out the exact how and why, <strong>studies show that high sugar and fat intake in animal models <a href=\"https:\/\/www.cell.com\/trends\/endocrinology-metabolism\/fulltext\/S1043-2760(20)30235-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1043276020302356%3Fshowall%3Dtrue\">dampens the responsiveness of taste cells<\/a> and <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(22)01212-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS096098222201212X%3Fshowall%3Dtrue\">nerves to sugars<\/a>, modifies the number of taste cells available, and even flips <a href=\"https:\/\/theconversation.com\/what-you-eat-can-reprogram-your-genes-an-expert-explains-the-emerging-science-of-nutrigenomics-165867\">genetic switches<\/a> in the <a href=\"https:\/\/doi.org\/10.7554\/eLife.83979\">taste cells\u2019 DNA<\/a>.<\/strong><\/p>\n<h2>Illness Can Also Influence Taste<\/h2>\n<p>Genetics and food aren\u2019t the only factors that affect taste, however.<\/p>\n<p>As many of us discovered <a href=\"https:\/\/theconversation.com\/covid-19-smell-and-taste-how-is-covid-19-different-from-other-respiratory-diseases-139543\">during the height of the COVID-19 pandemic<\/a>, <a href=\"https:\/\/doi.org\/10.1038%2Fs41598-022-11864-8\">disease can also play a role<\/a> in taste perception. After testing positive for COVID-19, I couldn\u2019t tell the difference between sweet, bitter, and sour foods for months.<\/p>\n<p>Researchers have found that about 40% of people infected with SARS-CoV-2 <a href=\"https:\/\/doi.org\/10.1093\/chemse\/bjac001\">experience impairment in taste and smell<\/a>. In about 5% of those people, these <a href=\"https:\/\/doi.org\/10.1136\/bmj-2021-069503\">taste deficits persist<\/a> for months and years.<\/p>\n<p><strong>Although researchers don\u2019t understand what causes these sensory alterations, the leading hypothesis is that the virus <a href=\"https:\/\/doi.org\/10.1038\/d41586-022-01627-w\">infects the cells that support the taste and smell receptors<\/a>.<\/strong><\/p>\n<h2>Training Taste Buds for Healthier Eating<\/h2>\n<figure id=\"attachment_57303\" aria-describedby=\"caption-attachment-57303\" style=\"width: 1254px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-57303\" src=\"https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-1173965821.jpg\" alt=\"Cheerful young Afro american woman eating vegetable salad at home. Close-up Of Beautiful African American Woman Eating Salad At Home. Beautiful woman on the sofa eating a healthy salad\" width=\"1254\" height=\"837\" srcset=\"https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=1254,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-1173965821.jpg 1254w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=300,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-1173965821-300x200.jpg 300w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=1024,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-1173965821-1024x683.jpg 1024w, https:\/\/cdn.foodrevolution.org\/cdn-cgi\/image\/width=768,quality=75,format=auto\/foodrevolution.org\/wp-content\/uploads\/iStock-1173965821-768x513.jpg 768w\" sizes=\"auto, (max-width: 1254px) 100vw, 1254px\" \/><figcaption id=\"caption-attachment-57303\" class=\"wp-caption-text\">iStock.com\/dragana001<\/figcaption><\/figure>\n<p>By shaping our eating habits, the intricate dance between genes, diet, disease, and taste can affect the risk of chronic diseases.<\/p>\n<p>Beyond distinguishing food from toxins, the brain uses taste signals as a proxy to estimate the filling power of foods. In nature, the stronger a food tastes \u2014 in terms of sweetness or <a href=\"\/blog\/salt-vs-sodium-facts\/\">saltiness<\/a> \u2014 is directly connected to its nutrient levels and calorie content. For example, a mango contains five times the amount of sugar than a cup of strawberries, so it tastes sweeter and is more filling. Thus, <strong>taste is important not just for food enjoyment and choice <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0031938421001116?via%3Dihub\">but also for regulating food intake<\/a>.<\/strong><\/p>\n<p>When taste is altered by diet or disease, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0031938415003303?via%3Dihub\">sensory and nutrient information could become \u201cdecoupled&#8221;<\/a> and no longer provide accurate information to our brains about portion size. Research shows this may also occur with the <a href=\"https:\/\/www.washingtonpost.com\/business\/2020\/03\/10\/common-artificial-sweetener-might-be-making-you-fatter-sicker-new-study-says\/\">consumption of<\/a> <a href=\"https:\/\/theconversation.com\/whos-recommendation-against-the-use-of-artificial-sweeteners-for-weight-loss-leaves-many-questions-unanswered-206175\">artificial sweeteners<\/a>.<\/p>\n<p>Indeed, in recent studies, our lab discovered that the changes in taste caused by <a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(19)30492-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124719304929%3Fshowall%3Dtrue\">high dietary sugar intake<\/a> <a href=\"https:\/\/doi.org\/10.7554\/eLife.54530\">drove higher eating<\/a> by <a href=\"https:\/\/www.cell.com\/current-biology\/fulltext\/S0960-9822(22)01829-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0960982222018292%3Fshowall%3Dtrue\">impairing these food predictions<\/a>. Notably, many eating patterns and brain changes we observed in flies have also been <a href=\"https:\/\/theconversation.com\/diet-can-influence-mood-behavior-and-more-a-neuroscientist-explains-185360\">discovered in<\/a> people who ate foods high in sugar or fat or had a high body mass index (BMI). This raises the question of whether these effects also arise from taste and sensory alterations in our brains.<\/p>\n<p>But there is a silver lining to the adaptable nature of taste. <strong>Since diet shapes our senses, we can train our taste buds and brains to <a href=\"https:\/\/doi.org\/10.1093\/advances\/nmaa151\">respond and prefer foods with lower quantities of sugar<\/a> and <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK50956\/\">salt<\/a>.<\/strong><\/p>\n<p>Interestingly, many people already say they <a href=\"https:\/\/monell.org\/big-data-says-food-is-too-sweet\/\">find foods overly sweet<\/a>, which may not be surprising since 60% to 70% of <a href=\"https:\/\/www.nytimes.com\/2016\/05\/22\/upshot\/it-isnt-easy-to-figure-out-which-foods-contain-sugar.html\">grocery store foods contain added sugar<\/a>. Reformulating foods tailored to our genes and the plasticity of our taste buds could be a practical and powerful tool to <a href=\"https:\/\/www.who.int\/publications\/i\/item\/924120916X\">enhance nutrition, promote health, and decrease the burden of chronic disease<\/a>.<\/p>\n<h4>Tell us in the comments:<\/h4>\n<ul>\n<li>How do you feel about salty, sweet, or bitter foods?<\/li>\n<li>Have you ever noticed a change in your taste preferences?<\/li>\n<\/ul>\n<p><i>Featured Image: iStock.com\/Liudmila Chernetska<\/i><\/p>\n<h4>Read Next:<\/h4>\n<div class=\"posts-slider-title\">\n<ul>\n<li class=\"entry-title\"><a href=\"https:\/\/foodrevolution.org\/blog\/sugar-temptation\/\">How to Avoid Temptation &amp; Slay the Sugary Beast<\/a><\/li>\n<li class=\"posts-slider-title\">\n<p class=\"entry-title\"><a href=\"https:\/\/foodrevolution.org\/blog\/salt-vs-sodium-facts\/\">Is Salt Good for You? Sodium Facts You Need To Know About<\/a><\/p>\n<\/li>\n<\/ul>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This article explores the fascinating interplay between genes, diet, and environment that shapes our sense of taste. Discover how neuroscientists&#8217; research reveals that our sense of taste can be dulled by illness or too much salt or sugar in our diets \u2014 and how we might retrain our taste buds for better health.<\/p>\n","protected":false},"author":162,"featured_media":57297,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,2638,2639,2641],"tags":[1016,164],"class_list":["post-57296","post","type-post","status-publish","format-standard","has-post-thumbnail","category-blog","category-food","category-health","category-nutrients","tag-food-addiction","tag-food-industry","wpautop"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Can We Train Our Taste Buds for Health?<\/title>\n<meta name=\"description\" content=\"Discover how researchers are working to identify how we can train our taste 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